Nanofat

纳米脂肪注射

什么是纳米脂肪注射?

纳米脂肪注射是一种减少细纹和皱纹的方法,通常用于改善面部肤质。纳米脂肪注射与一般的填充注射无异,差别在于使用的填充物是自体脂肪(受体本身的脂肪细胞)。

脂肪移植(或脂肪转移)并不是一种全新的手术。事实上,使用移植脂肪来提升面部,让面部看起来更加丰盈饱满的整形手术已经存在了很长时间,且随着时间的推移,技术和方法已经得到改进。

然而,纳米脂肪的问世代表了脂肪移植方法的巨大跃进。我们现在能够使用极细的导管针,在眼睛下方和嘴唇周围注射纳米脂肪来抚平细纹。在某种程度上,这得归功于脂肪干细胞(ADSCs,也称为间充质干细胞)和纳米脂肪中的生长因子,才能让皮肤收益。

随着技术的发展,人们已能将脂肪细胞转化为微小的粒子,从而开辟了许多新的可能性。因此,在过去几年中,脂肪移植领域再次受到青睐。

纳米脂肪注射带来哪些成果?

纳米脂肪注射可以减少细纹和皱纹,改善皮肤质量。最近的研究还表明,纳米脂肪可以改善老旧疤痕的外观(点击此处阅读参考文章)。

此外,将纳米脂肪与小颗粒脂肪(MilliFat)及微粒脂肪(MicroFat)联合使用,还可以逆转衰老迹象。纳米脂肪注射唯一无法改善的是色素沉着,但它可以修复因太阳(或紫外线)照射造成的皮肤损伤。

脂肪移植通常也用于增强埋线拉提或某些免动刀面部拉皮疗法(如 超声刀Ulthera热玛吉)的效果

Fat grafting

脂肪移植手术是如何进行的?

脂肪移植手术过程涉及在局部麻醉的情况下,从腹部或大腿内侧抽取脂肪,基本上是一种小型抽脂

然后将脂肪净化、提纯并分离成不同大小的细胞——小颗粒脂肪、微粒脂肪或纳米脂肪。接着,使用David Loh博士发布的一项技术,将较大的脂肪细胞用来重新激活和提拉面部肌肤。该技术通常被称为DL提拉

最小的脂肪细胞是纳米脂肪,用于减少细纹和皱纹,或者改善一般皮肤质量。

我们拥有用于纳米脂肪注射的专利封闭系统。在抽取、提纯到重新注射纳米脂肪的整个过程中,脂肪细胞完全不会受到环境污染。

手术后,脂肪提取处会有一些瘀伤和不适,可能需要几天到一周才能恢复。总体上,这种不适通常比较轻微。

移植了脂肪后,面部也会有轻微肿胀(我估计约为20%肿大),并且略微敏感(触摸时伴有疼痛)。同时可能会出现一些瘀伤,但总体而言,恢复过程仍算得上舒适。

移植的脂肪可以保持多长时间?

脂肪被移植到新的环境后,有一定比例不会被吸收并将经历细胞凋亡。至于面部,由于血液供应丰富,移植脂肪细胞存活率相当高,预计为40%-60%。因此,我们只需要多移植一点就可以达到预期效果。

大约一个月后,存活下来的所有脂肪细胞都会永远保留下来。它们将融入面部,并将永久抵抗岁月的摧残。事实上,他们会随着极端的体重波动扩展和收缩。


Read more about Liposuction, Vaser Liposelection, Liposuction Not being a method of Weight Reduction, but instead Liposuction being more about a sense of proportion

And did you know we can correct over done fat transfers (fat grafting)?

 

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Nanofat

5 things to know about Nanofat Grafting

Fat grafting is a long established technique in cosmetic surgery; probably for as long as liposuction has been available. And that’s since the later part of the 1980s.

What’s new is that we can now select the smallest particles of fat cells (Nanofat), and use them to erase lines and wrinkles, as well as to improve skin quality. Some researchers have referred to them as stem-cell-like fractions called Stromal Vascular Fraction (SVF) or Mesenchymal Stem Cells (MSCs).

1. WHAT IS NANOFAT GRAFTING?

Nanofat injection is a method to reduce fine lines and wrinkles, or generally to improve skin quality in the face.

Nanofat is delivered like a filler injection except in this case the material used is autologous fat (one’s own fat cells).

Fat grafting (or fat transfers) are not exactly a new procedure. The procedure where grafted fat is used to volumize and lift the face, has been around for a long time. Of course, techniques and methods have improved over time. However, the advent of Nanofat represents a quantum leap in Fat Grafting methods. We are now able to treat even the fine lines under the eyes and around the mouth using Nanofat delivered with a very fine cannula.

Nanofats are actually the smallest particles of fat cells, which will survive best in a transplant scenario. The skin benefits are believed to be at least partially due to the stem-cells and growth factors in the Nanofat.

The ability to micronize fat cells down to very fine spheres has opened up many new possibilities, and as such the field of fat grafting has re-gained in popularity in the last few years.

2. WHAT IS NANOFAT USED FOR?

Nanofat can deliver skin quality improvements like the reduction of fine lines and wrinkles.

Recent studies have also shown that nanofat can improve the appearance of old scars (reference article – click here). (Updated in 2021 in The Plastic Reconstructive Journal: Adipose-derived stromal vascular fraction, or more commonly referred to as Nanofat, can improve skin quality via increased collagen production, and resist UV induced skin damage when injected into the dermis of the skin.

Used together with MilliFat and MicroFat, which provide structural support for the sagging face, we can reverse a host of the signs related to ageing. The only thing it does not treat is pigmentation. But it can even reverse skin damage due to sun (or UV) exposure.

Fat grafting is often used to enhance the effects of a threadlift or some non-surgical facelift like Ultherapy and Thermage.

3. WHAT IS THE FAT GRAFTING PROCEDURE LIKE?

The procedure involves harvesting fat from the abdomen or the inner thighs under local anaesthetic – essentially a mini-liposuction.

The fat is then cleaned, filtered and separated into different size cells – MilliFat, MicroFat or NanoFat. The larger fat cells are used to revolumize and lift the face, a kind of structural support, using a technique that Dr David Loh published. The technique has been commonly called the DL Lift.

The smallest of the fat cells are the Nanofat. They are used for the reduction of lines and wrinkles. Or for general skin quality improvements.

During the whole process from extraction, filtration to re-injection, the fat cells are completely free from environmental contamination (scientific jargon: closed system). We have a patented closed system for nanofat injections.

Post procedure, there will be some bruising and discomfort in the donor area (the area where fat was harvested in a mini-liposuction). This may take a few days to a week to recover. The overall discomfort is generally mild.

The face where the fat has been grafted will also be slighted swollen (about 20% bigger, I would say), and be slightly tender (sore to touch). Some bruising is to be expected, but again the overall recovery process is quite comfortable.

4. HOW LONG CAN THE GRAFTED FAT LAST?

A certain percentage of the transplanted fat will not take in the new environment and undergo apoptosis. Usually for the face, because of the rich blood supply, graft survival rates are quite high. You can expect somewhere in the region of 40%-60% grafted fat survival rates. So, we only need to over transplant by a little to achieve the desired outcomes.

After about one-month, whatever fat cells that remain will last forever. They will have been incorporated into the face and will last forever barring the ravages of time. In fact, they will expand and contract with extremes of weight fluctuations.

5. HOW DOES FAT GRAFTING PRICE COMPARE WITH DERMAL FILLERS?

When we do a fat grafting procedure, it is always a full face procedure. Meaning we treat the forehead, temples, cheeks and even the chin. And we harvest nanofat to treat the undereye and perioral areas too. The reason being that we want to maximize the areas treated because a mini-liposuction is involved each time. Multiple syringes of dermal fillers would be needed in order to treat similar areas. Maybe of the order of 8-12 syringes. At $1000 per syringe, you can imagine the cost even if we give discounts when multiple syringes are used. See your price list

Fat grafting (structural augmentation and nanofat grafting) costs $4,000 before GST. That’s it. And a proportion of the fat will stay for the long term.

The only “shortcoming” with fat grafting is that certain areas that need stronger structural support like the chin and the nose, harder HA fillers like Volux might still be better. In order to achieve the kind of projection needed for such areas.


Read more about Liposuction, Vaser Liposelection, Liposuction Not being a method of Weight Reduction, but instead Liposuction being more about a sense of proportion

And did you know we can correct over done fat transfers (fat grafting)?

WhatsApp us on +65 9153 1503 for more on fat grafting, nanofat grafting, and stromal vascular fractions (adipose derived stem cells). 

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correcting fat transfers

Smartlipo to the Rescue. Correcting Over-done Fat Transfers

DID YOU KNOW THAT OVERDONE FAT-TRANSFERS CAN BE CORRECTED?

While Fat Transfer (aka Fat Grafting or Lipofilling) on the face is a relatively easy task for doctors with the setup for office-based liposuction, getting it just right is not always a given. There are many variables like the quality of the fat after liposuction; the quality of the skin on the face which will determine the blood supply available to support the fat;  the age of the patient; whether a smoker or not …and so forth.

I have been doing fat transfers since 2007 and I have had more than a few requests in the past to treat the overfilled foreheads, chins, and overfilled cheeks. Some were my patients, but mostly were done overseas – mainly in the country that is now very popular for cosmetic surgery. Not that their doctors are bad, I guess it must be too inconvenient to fly there to do corrections, hence they land up for corrections with me. The pros and cons of medical tourism for invasive procedures is of course a topic for another blog altogether in itself.

Our Smartlipo system is just ideal for this purpose. The technology started me on the road to liposuction in 2006, and now although I have moved on to more efficient and effective systems to do liposuction, I still fall back on Smartlipo to do small and delicate areas. Smartlipo gives me accuracy and precision to treat small areas like overfilled foreheads, cheeks and chins.

The fibre-optic system delivers pulses of laser to melt away excess fat. In doing so, I can partially or fully remove the overfilled areas. It’s almost like the “Eraser” for Fat Fillers.

Dr David Loh

Read more about fat grafting (fat transfers) to the face

 

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